Novel mutation in 16S rRNA associated with streptomycin dependence in Mycobacterium tuberculosis.
1995
Abstract
Molecular characterization of a streptomycin-dependent mutant of Mycobacterium tuberculosis revealed the presence of a novel mutation in the rrs gene encoding 16S rRNA. Insertion of an additional cytosine in the 530 loop of 16S rRNA, a region known to be involved in streptomycin susceptibility and resistance, was associated with streptomycin dependence.
Details
Title
Novel mutation in 16S rRNA associated with streptomycin dependence in Mycobacterium tuberculosis.
Author(s)
Honoré, N ; Marchal, G ; Cole, S T
Published in
Antimicrobial agents and chemotherapy
Volume
39
Issue
3
Pages
769-770
Date
1995
ISSN
0066-4804
Other identifier(s)
View record in PubMed
Laboratories
UPCOL
Record Appears in
Scientific production and competences > SV - School of Life Sciences > SV Archives > UPCOL - Prof. Cole Group
Peer-reviewed publications
Work outside EPFL
Journal Articles
Published
Peer-reviewed publications
Work outside EPFL
Journal Articles
Published
Record creation date
2010-09-07