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000151272 005__ 20190316234848.0
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000151272 245__ $$a[What can be expected from sequencing of the Mycobacterium tuberculosis genome?]
000151272 269__ $$a2000
000151272 260__ $$c2000
000151272 336__ $$aJournal Articles
000151272 520__ $$aMycobacterium tuberculosis, the scourge of humanity, is one of the most successful and scientifically challenging pathogens of all time. To catalyze the conception of new prophylactic and therapeutic interventions against tuberculosis, and to enhance our understanding of the biology of the tubercle bacillus, the complete genome sequence of the most widely used strain, H37Rv, has been determined. Bioinformatic analysis led to the identification of approximately 4,000 genes in the 4.41 Mb genome sequence and provided fresh insight into the biochemistry, physiology, genetics and immunology of this much-feared bacterium. Genomic information is centralised in TubercuList (http://www.pasteur.fr/Biol/TubercuList/).
000151272 6531_ $$aGenome, Bacterial
000151272 700__ $$g177247$$aCole, S T$$0243892
000151272 773__ $$j183$$tBulletin de l'Académie nationale de médecine$$k7$$q41-50; discussion 50-1
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000151272 937__ $$aEPFL-ARTICLE-151272
000151272 973__ $$rREVIEWED$$sPUBLISHED$$aOTHER
000151272 980__ $$aARTICLE