000151225 001__ 151225
000151225 005__ 20181203021957.0
000151225 022__ $$a1462-5814
000151225 02470 $$2PMID$$a15953026
000151225 0247_ $$2doi$$a10.1111/j.1462-5822.2005.00521.x
000151225 037__ $$aARTICLE
000151225 245__ $$aColonization of the salivary glands of Naucoris cimicoides by Mycobacterium ulcerans requires host plasmatocytes and a macrolide toxin, mycolactone
000151225 269__ $$a2005
000151225 260__ $$c2005
000151225 336__ $$aJournal Articles
000151225 520__ $$aMycobacterium ulcerans was first identified as the causative agent of Buruli ulcer; this cutaneous tissue-destructive process represents the third most important mycobacterial disease in humans after tuberculosis and leprosy. More recently other life traits were documented. M. ulcerans is mainly detected in humid tropical zones as part of a complex ecosystem comprising algae, aquatic insect predators of the genus Naucoris, and very likely their vegetarian preys. Coelomic plasmatocytes could be the first cells of Naucoris cimicoides to be involved in the infection process, acting as shuttle cells that deliver M. ulcerans to the salivary glands as suggested by both in vitro and in vivo approaches. Furthermore, a key element for the early and long-term establishment of M. ulcerans in Naucoridae is demonstrated by the fact that only mycolactone toxin-producing M. ulcerans isolates are able to invade the salivary glands, a site where they proliferate. Later, the raptorial legs of Naucoris are covered by M. ulcerans-containing material that displays features of biofilms.
000151225 700__ $$aMarsollier, Laurent
000151225 700__ $$aAubry, Jacques
000151225 700__ $$aCoutanceau, Emmanuelle
000151225 700__ $$aAndré, Jean-Paul Saint
000151225 700__ $$aSmall, Pamela L
000151225 700__ $$aMilon, Geneviève
000151225 700__ $$aLegras, Pierre
000151225 700__ $$aGuadagnini, Stéphanie
000151225 700__ $$aCarbonnelle, Bernard
000151225 700__ $$g177247$$aCole, Stewart T$$0243892
000151225 773__ $$j7$$tCellular microbiology$$k7$$q935-43
000151225 909C0 $$xU11742$$0252302$$pUPCOL
000151225 909CO $$pSV$$particle$$ooai:infoscience.tind.io:151225
000151225 937__ $$aEPFL-ARTICLE-151225
000151225 973__ $$rREVIEWED$$sPUBLISHED$$aOTHER
000151225 980__ $$aARTICLE