000150719 001__ 150719
000150719 005__ 20190316234844.0
000150719 020__ $$a978-1-4244-6842-3
000150719 037__ $$aCONF
000150719 245__ $$aCarbon Nanotubes-Based Electrochemical Sensing for Cell Culture Monitoring
000150719 269__ $$a2010
000150719 260__ $$c2010
000150719 336__ $$aConference Papers
000150719 520__ $$aMonitoring of metabolic compounds, such as glucose and lactate, is extensively reported in literature, especially for clinical purposes. Instead, the application of such technologies for monitoring metabolites in cell cultures has not been explored. From one side, such devices can provide information to the current state-of-the-art of cell lines, particularly those which are not fully known, as stem and embryonic cells. On the other hand, those systems can pave the way to fully automation for growing cell cultures, when coupled with robots for feeding. Among different presented strategies to develop biosensors,carbon nanotubes exhibit great properties, particularly suitable for biosensing. In this work nanostructured electrodes by using multi-walled carbon nanotubes are presented for the detection of glucose and lactate. Firstly, some results from simulations are illustrated in order to foresee the behavior of carbon nanotubes depending on their orientation, when they are dispersed onto the electrode surface. Then, such developed biosensors are characterized in terms of sensitivity and detection limit, and are compared to previously published results. Finally, monitoring of a cell culture is performed and the behavior of metabolites is analyzed as biosensors validation.
000150719 700__ $$0242418$$g176461$$aBoero, Cristina
000150719 700__ $$0242413$$g182237$$aCarrara, Sandro
000150719 700__ $$aDel Vecchio, Giovanna
000150719 700__ $$aAlbini, Giuseppe D.
000150719 700__ $$aCalzà, Laura
000150719 700__ $$0240269$$g167918$$aDe Micheli, Giovanni
000150719 7112_ $$dJuly 13-15, 2010$$cGold Coast, Australia$$a2010 IEEE/ICME International Conference on Complex Medical Engineering
000150719 773__ $$j1$$tProceedings of the 2010 IEEE/ICME International Conference on Complex Medical Engineering$$q288-293
000150719 8564_ $$uhttps://infoscience.epfl.ch/record/150719/files/2010_icme_boero_conf.pdf$$zn/a$$s174406$$yn/a
000150719 909C0 $$xU11140$$0252283$$pLSI1
000150719 909CO $$pIC$$qGLOBAL_SET$$ooai:infoscience.tind.io:150719$$pconf$$pSTI
000150719 917Z8 $$x176271
000150719 937__ $$aEPFL-CONF-150719
000150719 973__ $$rREVIEWED$$sPUBLISHED$$aEPFL
000150719 980__ $$aCONF