Carbon Dioxide as the C1 Source for Direct C−H Functionalization of Aromatic Heterocycles

A simple and straightforward method has been developed for the direct carboxylation of aromatic heterocylces such as oxazoles, thiazoles, and oxadiazoles using CO2 as the C1 source. The reactions require no metal catalyst and only Cs2CO3 as the base. A good functional group tolerance is achieved.


Published in:
Organic Letters, 12, 15, 3567–3569
Year:
2010
Publisher:
American Chemical Society
ISSN:
1523-7060
Keywords:
Laboratories:


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 Record created 2010-07-16, last modified 2018-03-17

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