Kinetics of Yttrium-Ligand Complexation Monitored Using Hyperpolarized 89Y as a Model for Gadolinium in Contrast Agents

Hyperpolarization by dissolution dynamic nuclear polarization (DNP) enhances Y-89 spin magnetization by 3 to 4 orders of magnitude and provides a way to monitor yttrium-ligand complexation "on the fly" by means of Y-89 NMR. In this communication, we show an example of free yttrium Y3+ being complexed with 1,4,7,10-tetrakis(acetamido)-1,4,7,10-tetraazacyclododecane (DOTAM) to form [Y(DOTAM)(H2O)](3+) as a model for gadolinium in contrast agents.


Published in:
Journal of the American Chemical Society, 132, 14, 5006-5007
Year:
2010
Publisher:
American Chemical Society
ISSN:
1520-5126
Keywords:
Laboratories:


Note: The status of this file is: EPFL only


 Record created 2010-04-26, last modified 2018-03-18

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