Deteriorated visual backward masking in the shine-through effect in adolescents with psychosis.
Visual backward masking is a reliable and widely used tool in schizophrenia research. Whereas many studies have shown masking deficits in adult patients, there are only very few studies with adolescents with psychosis-and with controversial results. Masking deficits of adolescents are of primary interest because they are not caused by long-term suffering from the disease and severe medication. We investigated 15 adolescents with psychosis and 19 age-matched controls in the shine-through backward masking paradigm for which strong performance deficits were shown previously in adult schizophrenic patients and their relatives. Adolescents with psychosis were strongly impaired in the shine-through effect compared to controls. This result adds further evidence that backward masking is an endophenotype of schizophrenia.
Keywords: Schizophrenia ; Perceptual disorders ; Visual processing ; Verniers ; Endophenotype ; Schizophrenia Spectrum Disorders ; Neuropsychological Status Rbans ; Negative-Symptom Schizophrenia ; Repeatable Battery ; Screening-Test ; Validity ; Endophenotypes ; Attention ; Deficits
Record created on 2010-03-23, modified on 2016-08-08