Deteriorated visual backward masking in the shine-through effect in adolescents with psychosis

Visual backward masking is a reliable and widely used tool in schizophrenia research. Whereas many studies have shown masking deficits in adult patients, there are only very few studies with adolescents with psychosis-and with controversial results. Masking deficits of adolescents are of primary interest because they are not caused by long-term suffering from the disease and severe medication. We investigated 15 adolescents with psychosis and 19 age-matched controls in the shine-through backward masking paradigm for which strong performance deficits were shown previously in adult schizophrenic patients and their relatives. Adolescents with psychosis were strongly impaired in the shine-through effect compared to controls. This result adds further evidence that backward masking is an endophenotype of schizophrenia.


Published in:
Journal of clinical and experimental neuropsychology, 31, 6, 641-7
Year:
2009
Publisher:
Taylor & Francis
ISSN:
1744-411X
Keywords:
Laboratories:




 Record created 2010-03-23, last modified 2018-03-17


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