Waveguide fluorosensor for the detection of ligand-receptor interactions - The 5-HT3 serotonin receptor

A highly-sensitive surface fluorescence technique was combined with a powerful method for the oriented reversible immobilization of membrane proteins on oxide surfaces. Affinity and kinetic parameters of the interaction of the receptor and a fluorescent ligand were evaluated. The approach is particularly suited for the study of rapid ligand-receptor interactions where optimized cell volume, flow and injection conditions are required.


Published in:
NOVEL APPROACHES IN BIOSENSORS AND RAPID DIAGNOSTIC ASSAYS, 135-145
Presented at:
43rd OHOLO Conference on Novel Applroaches in Biosensors and Rapid Diagnostic Assays, Elat, Isareal, 1999
Year:
1999
Publisher:
NEW YORK, KLUWER ACADEMIC/PLENUM PUBL
ISBN:
0-306-46444-6
Laboratories:




 Record created 2010-03-17, last modified 2018-03-17


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