Biomechanics in bone tissue engineering

Biomechanics may be considered as central in the development of bone tissue engineering. The initial mechanical aspects are essential to the outcome of a functional tissue engineering approach, so are aspects of interface micromotion, bone ingrowths inside the scaffold and finally the mechanical integrity of the scaffold during its degradation. A proposed view is presented herein on how biomechanical aspects can be synthesized and where future developments are needed. In particular, a distinction is made between the mechanical and the mechanotransductional aspects in bone tissue engineering: the former could be related to osteoconduction, while the later may be correlated to the osteoinductive properties of the scaffold. This distinction allows biomechanicians to follow a strategy in the development of a scaffold having not only mechanical targets, but also incorporating some mechanotransduction principles.


Publié dans:
Computer Methods In Biomechanics And Biomedical Engineering, 13, 837-846
Année
2010
Publisher:
Taylor & Francis
ISSN:
1025-5842
Mots-clefs:
Laboratoires:




 Notice créée le 2010-01-19, modifiée le 2019-02-05

n/a:
Télécharger le document
PDF

Évaluer ce document:

Rate this document:
1
2
3
 
(Pas encore évalué)