000143440 001__ 143440
000143440 005__ 20190316234652.0
000143440 0247_ $$2doi$$a10.1080/10255841003630660
000143440 022__ $$a1025-5842
000143440 02470 $$2ISI$$a000285145800022
000143440 037__ $$aARTICLE
000143440 245__ $$aBiomechanics in bone tissue engineering
000143440 269__ $$a2010
000143440 260__ $$bTaylor & Francis$$c2010
000143440 336__ $$aJournal Articles
000143440 520__ $$aBiomechanics may be considered as central in the development of bone tissue engineering. The initial mechanical aspects are essential to the outcome of a functional tissue engineering approach, so are aspects of interface micromotion, bone ingrowths inside the scaffold and finally the mechanical integrity of the scaffold during its degradation. A proposed view is presented herein on how biomechanical aspects can be synthesized and where future developments are needed. In particular, a distinction is made between the mechanical and the mechanotransductional aspects in bone tissue engineering: the former could be related to osteoconduction, while the later may be correlated to the osteoinductive properties of the scaffold. This distinction allows biomechanicians to follow a strategy in the development of a scaffold having not only mechanical targets, but also incorporating some mechanotransduction principles.
000143440 6531_ $$abone scaffold
000143440 6531_ $$aload-bearing application
000143440 6531_ $$abiomechanics
000143440 6531_ $$amechanotransduction
000143440 6531_ $$atissue engineering
000143440 6531_ $$aMesenchymal Stem-Cells
000143440 6531_ $$aFinite-Element
000143440 6531_ $$aOsteogenic Differentiation
000143440 6531_ $$aBiophysical Principles
000143440 6531_ $$aMechanical-Properties
000143440 6531_ $$aTrabecular Bone
000143440 6531_ $$aFluid-Flow
000143440 6531_ $$aIn-Vitro
000143440 6531_ $$aScaffolds
000143440 6531_ $$aRegeneration
000143440 700__ $$0240508$$aPioletti, Dominique P.$$g103117
000143440 773__ $$j13$$q837-846$$tComputer Methods In Biomechanics And Biomedical Engineering
000143440 8564_ $$s277321$$uhttps://infoscience.epfl.ch/record/143440/files/CMBBE%28Domi%29.pdf$$yn/a$$zn/a
000143440 909C0 $$0252108$$pLBO$$xU10299
000143440 909CO $$ooai:infoscience.tind.io:143440$$pSTI$$particle$$qGLOBAL_SET
000143440 917Z8 $$x103117
000143440 917Z8 $$x148230
000143440 937__ $$aLBO-ARTICLE-2010-001
000143440 973__ $$aEPFL$$rREVIEWED$$sPUBLISHED
000143440 980__ $$aARTICLE