000143197 001__ 143197
000143197 005__ 20181228151102.0
000143197 022__ $$a0304-3940
000143197 02470 $$2PMID$$a7792053
000143197 0247_ $$2doi$$a10.1016/0304-3940(95)11410-X
000143197 037__ $$aARTICLE
000143197 245__ $$aAdenosine triphosphate and arachidonic acid stimulate glycogenolysis in primary cultures of mouse cerebral cortical astrocytes
000143197 269__ $$a1995
000143197 260__ $$c1995
000143197 336__ $$aJournal Articles
000143197 520__ $$aAdenosine triphosphate (ATP) promotes glycogenolysis in primary cultures of mouse cerebral cortical astrocytes with an EC50 of 1.5 microM. A pharmacological analysis indicates an involvement of purinergic P2Y receptors in this action of ATP. Application of either arachidonic acid (AA), or certain unsaturated fatty acids, also results in glycogen breakdown. The EC50 of AA is approximately 50 microM. Thus ATP and AA can be added to the list of neuroactive agents that control glycogen levels in astrocytes, which includes noradrenaline, vasoactive intestinal peptide (VIP), adenosine and histamine.
000143197 700__ $$aSorg, O
000143197 700__ $$aPellerin, L
000143197 700__ $$aStolz, M
000143197 700__ $$aBeggah, S
000143197 700__ $$g134990$$aMagistretti, P J$$0243698
000143197 773__ $$j188$$tNeuroscience letters$$k2$$q109-12
000143197 909C0 $$xU11150$$0252265$$pLNDC
000143197 909CO $$qSV$$particle$$ooai:infoscience.tind.io:143197
000143197 937__ $$aLNDC-ARTICLE-1995-005
000143197 973__ $$rREVIEWED$$sPUBLISHED$$aOTHER
000143197 980__ $$aARTICLE