000142849 001__ 142849
000142849 005__ 20180913055552.0
000142849 0247_ $$2doi$$a10.1055/s-0029-1218608
000142849 02470 $$2ISI$$a000274246100011
000142849 037__ $$aARTICLE
000142849 245__ $$aSynthetic Studies on the Sporolides: Exploration of the Enediyne Route
000142849 269__ $$a2010
000142849 260__ $$c2010
000142849 336__ $$aJournal Articles
000142849 520__ $$aSynthetic studies towards the construction of the cyclopenta[a]indene fragment of the heptacyclic marine metabolite sporolide are reported based on a hypothetical biosynthesis. The key step of this biogenetic proposal includes a Bergman cyclization of an enediyne precursor. The enediyne target of this synthetic study was prepared by Sonogashira cross-coupling of two fragments, of which the cyclopentane fragment was prepared from cyclopentenone, Morita-Baylis-Hillman reaction, and enantioselective Sharpless dihydroxylation.
000142849 6531_ $$across-coupling
000142849 6531_ $$anatural products
000142849 6531_ $$aoxidations
000142849 6531_ $$astereo­selective synthesis
000142849 6531_ $$atotal synthesis
000142849 700__ $$aBonazzi, Simone
000142849 700__ $$aBinaghi, Massimo
000142849 700__ $$aFellay, Cindy
000142849 700__ $$aWach, Jean-Yves
000142849 700__ $$0240224$$aGademann, Karl$$g167984
000142849 773__ $$k4$$q631-642$$tSynthesis
000142849 909C0 $$0252078$$pLSYNC$$xU11423
000142849 909CO $$ooai:infoscience.tind.io:142849$$pSB$$particle
000142849 937__ $$aLSYNC-ARTICLE-2009-011
000142849 973__ $$aEPFL$$rREVIEWED$$sPUBLISHED
000142849 980__ $$aARTICLE