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A novel liquid scintillation detector with high spatial resolution is being developed with standard microfabrication techniques. It consists of a dense array of scintillating waveguides obtained by filling microfluidic channels with an organic liquid scintillator and optically coupled to a pixellated photodetector. Such a microfluidic device can be designed and processed to meet the requirements of a wide range of applications like medical imaging, homeland security and high-energy physics. High-spatial resolution miniaturized detectors as well as large-area detectors can easily be fabricated. The fabrication process of a prototype detector and experimental results are presented in this paper.