Non-invasive dry mass determination and monitoring at the single cell level with digital holographic microscopy
Digital holography microscopy (DHM) is an optical microscopy technique which allows recording non-invasively the phase shift induced by living cells with nanometric sensitivity. Here, we exploit the phase signal as an indicator of dry mass (related to the protein concentration). This parameter allows monitoring the protein production rate and its evolution during the cell cycle.
Record created on 2009-07-20, modified on 2016-08-08