In situ measurements of human articular cartilage stiffness by means of a scanning force microscope

Osteoarthritis is a painful and disabling progressive joint disease, characterized by degradation of articular cartilage. In order to study this disease at early stages, we have miniaturized and integrated a complete scanning force microscope into a standard arthroscopic device fitting through a standard orthopedic canula. This instrument will allow orthopedic surgeons to measure the mechanical properties of articular cartilage at the nanometer and micrometer scale in-vivo during a standard arthroscopy. An orthopedic surgeon assessed the handling of the instrument. First measurements of the elasticity-modulus of human cartilage were recorded in a cadaver knee non minimal invasive. Second, minimally invasive experiments were performed using arthroscopic instruments. Load-displacement curves were successfully recorded. © 2007 IOP Publishing Ltd.


Published in:
Journal of Physics: Conference Series, 61, 1, 467-471
Year:
2007
ISSN:
17426588
Note:
406
Laboratories:




 Record created 2009-05-12, last modified 2018-03-17


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