PPAR gamma: an essential role in metabolic control

The peroxisome proliferator-activated receptor gamma is a nuclear hormone receptor playing a crucial role in adipogenesis and insulin sensitization. Prostaglandin J2 derivatives and the antidiabetic thiazolidinediones are its respective natural and synthetic ligands. The RXR/PPAR gamma heterodimer has also been reported to have important immunomodulatory activities and its pleiotropic functions suggest wide-ranging medical implications.


Published in:
Nutrition, metabolism, and cardiovascular diseases : NMCD, 11, 1, 64-9
Year:
2001
ISSN:
0939-4753
Keywords:
Other identifiers:
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 Record created 2009-04-02, last modified 2018-03-17


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