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review article
Mineral and bone metabolism in thyroid disease: a review
This review discusses the abnormalities in bone and mineral metabolism encountered in thyroid disorders. Thyroid hormones probably stimulate bone resorption directly, thereby increasing serum calcium and phosphorus concentrations and suppressing serum parathyroid hormone and 1,25-dihydroxyvitamin D3 concentrations. The decrease in these bone-resorbing hormones limits further increase in serum calcium concentration but also results in an enhanced intestinal calcium absorption. Such a negative calcium balance will eventually lead to hyperthyroid osteopenia. In adult hypothyroidism the opposite effects are seen.
Type
review article
PubMed ID
3774957
Authors
Publication date
1986
Published in
Volume
60
Issue
232
Start page
737
End page
752
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
April 2, 2009
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