Mouse phenogenomics: the fast track to "systems metabolism"

With the completion of the many genomes, genetics is positioned to meet physiology. In this review, we summarize the coming of "systems metabolism" in mammals through the use of the mouse, as a model system to study metabolism. Building on mouse genetics with increasingly sophisticated clinical and molecular phenotyping strategies has enabled scientists to now tackle complex biomedical questions, such as those related to the pathogenesis of the common metabolic disorders. The ultimate goal of such strategies will be to mimic human metabolism with the click of a mouse.


Published in:
Cell metabolism, 2, 6, 349-60
Year:
2005
ISSN:
1550-4131
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Other identifiers:
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Note: The status of this file is: Involved Laboratories Only


 Record created 2009-04-02, last modified 2018-03-17

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