About lipids and toxins

Many mono or multicellular organisms secrete soluble proteins, referred to as protein toxins, which alter the behavior of foreign, or target cells, possibly leading to their death. These toxins affect either the cell membrane by forming pores or modifying lipids, or some intracellular target. To reach this target, they must cross one of the cellular membranes, generally that of an intracellular organelle. As described in this minireview, lipids play crucial roles in the intoxication process of most if not all toxins, by allowing/promoting binding, endocytosis, trafficking and/or translocation into the cytoplasm


Published in:
FEBS Lett, 580, 23, 5572-9
Year:
2006
Note:
Author address: Ecole Polytechnique de Lausanne, Institute of Global Health, 1015 Lausanne, Switzerland
Other identifiers:
Laboratories:




 Record created 2009-02-02, last modified 2018-03-17


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