Adventures of a pore-forming toxin at the target cell surface

The past three years have shed light on how the pore-forming toxin aerolysin binds to its target cell and then hijacks cellular devices to promote its own polymerization and pore formation. This selective permeabilization of the plasma membrane has unexpected intracellular consequences that might explain the importance of aerolysin in Aeromonas pathogenicity


Published in:
Trends Microbiol, 8, 4, 168-72
Year:
2000
Note:
Author address: Dept of Biochemistry, University of Geneva, 30 quai E. Ansermet, 1211 Geneva 4, Switzerland
Laboratories:




 Record created 2009-02-02, last modified 2018-03-17


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