000130155 001__ 130155
000130155 005__ 20181203021343.0
000130155 0247_ $$2doi$$a10.1016/j.ccr.2008.01.009
000130155 02470 $$2ISI$$a000259897800011
000130155 02470 $$2DAR$$a13216
000130155 037__ $$aARTICLE
000130155 245__ $$aLigand exchange and complex formation kinetics studied by NMR exemplified on fac-[(CO)3M(H2O)]+ (M = Mn, Tc, Re)
000130155 269__ $$a2008
000130155 260__ $$c2008
000130155 336__ $$aJournal Articles
000130155 500__ $$aInvited Review
000130155 520__ $$aIn this review ligand exchange and complex formation reactions on fac-[(CO)3M(H2O)3]+ (M = Mn, Tc, Re) and on fac-[(CO)2(NO)Re(H2O)3]2+ are presented. A variety of experimental NMR techniques are described and it is shown that sometimes combinations of techniques applied at variable temperature or variable pressure allowed to measure exchange rate constants and their activation parameters as well as thermodynamic parameters. Furthermore, the use of uncommon nuclei for NMR like 17O or 99Tc extends considerably the range of applications especially in aqueous solutions when 1H NMR is often not very useful. Tricarbonyl triaqua complexes of technetium(I) and rhenium(I) became important precursors for a variety of radiopharmaceuticals under development. It has been shown that the fac-[(CO)3M]-unit is kinetically inert and thatwater molecules bound to it can be easily replaced. Reactivity of the ReI complexes is one to two orders of magnitude slower than its TcI analogues. Furthermore, it shows a marked acidity dependence which has not been observed for TcI and MnI species.
000130155 6531_ $$aNMR
000130155 6531_ $$aLigand exchange reactions
000130155 6531_ $$aComplex formation
000130155 6531_ $$aRadiopharmacy
000130155 6531_ $$aCarbonyl
000130155 700__ $$0240250$$aHelm, Lothar$$g144957
000130155 773__ $$j252$$q2346-2361$$tCoordination Chemistry Reviews
000130155 8564_ $$s1759963$$uhttps://infoscience.epfl.ch/record/130155/files/CCR252-2346.pdf$$zn/a
000130155 909C0 $$0252059$$pLCIB$$xU10103
000130155 909CO $$ooai:infoscience.tind.io:130155$$pSB$$particle
000130155 937__ $$aLCIB-ARTICLE-2008-040
000130155 973__ $$aEPFL$$rREVIEWED$$sPUBLISHED
000130155 980__ $$aARTICLE