Distributed Video Coding (DVC) is a new paradigm for video compression based on the information theoretical results of Slepian and Wolf (SW), and Wyner and Ziv (WZ). While conventional coding has a rigid complexity allocation as most of the complex tasks are performed at the encoder side, DVC enables a flexible complexity allocation between the encoder and the decoder. The most novel and interesting case is low complexity encoding and complex decoding, which is the opposite of conventional coding. While the latter is suitable for applications where the cost of the decoder is more critical than the encoder's one, DVC opens the door for a new range of applications where low complexity encoding is required and the decoder's complexity is not critical. This is interesting with the deployment of small and battery-powered multimedia mobile devices all around in our daily life. Further, since DVC operates as a reversed-complexity scheme when compared to conventional coding, DVC also enables the interesting scenario of low complexity encoding and decoding between two ends by transcoding between DVC and conventional coding. More specifically, low complexity encoding is possible by DVC at one end. Then, the resulting stream is decoded and conventionally re-encoded to enable low complexity decoding at the other end. Multiview video is attractive for a wide range of applications such as free viewpoint television, which is a system that allows viewing the scene from a viewpoint chosen by the viewer. Moreover, multiview can be beneficial for monitoring purposes in video surveillance. The increased use of multiview video systems is mainly due to the improvements in video technology and the reduced cost of cameras. While a multiview conventional codec will try to exploit the correlation among the different cameras at the encoder side, DVC allows for separate encoding of correlated video sources. Therefore, DVC requires no communication between the cameras in a multiview scenario. This is an advantage since communication is time consuming (i.e. more delay) and requires complex networking. Another appealing feature of DVC is the fact that it is based on a statistical framework. Moreover, DVC behaves as a natural joint source-channel coding solution. This results in an improved error resilience performance when compared to conventional coding. Further, DVC-based scalable codecs do not require a deterministic knowledge of the lower layers. In other words, the enhancement layers are completely independent from the base layer codec. This is called the codec-independent scalability feature, which offers a high flexibility in the way the various layers are distributed in a network. This thesis addresses the following topics: First, the theoretical foundations of DVC as well as the practical DVC scheme used in this research are presented. The potential applications for DVC are also outlined. DVC-based schemes use conventional coding to compress parts of the data, while the rest is compressed in a distributed fashion. Thus, different conventional codecs are studied in this research as they are compared in terms of compression efficiency for a rich set of sequences. This includes fine tuning the compression parameters such that the best performance is achieved for each codec. Further, DVC tools for improved Side Information (SI) and Error Concealment (EC) are introduced for monoview DVC using a partially decoded frame. The improved SI results in a significant gain in reconstruction quality for video with high activity and motion. This is done by re-estimating the erroneous motion vectors using the partially decoded frame to improve the SI quality. The latter is then used to enhance the reconstruction of the finally decoded frame. Further, the introduced spatio-temporal EC improves the quality of decoded video in the case of erroneously received packets, outperforming both spatial and temporal EC. Moreover, it also outperforms error-concealed conventional coding in different modes. Then, multiview DVC is studied in terms of SI generation, which differentiates it from the monoview case. More specifically, different multiview prediction techniques for SI generation are described and compared in terms of prediction quality, complexity and compression efficiency. Further, a technique for iterative multiview SI is introduced, where the final SI is used in an enhanced reconstruction process. The iterative SI outperforms the other SI generation techniques, especially for high motion video content. Finally, fusion techniques of temporal and inter-view side informations are introduced as well, which improves the performance of multiview DVC over monoview coding. DVC is also used to enable scalability for image and video coding. Since DVC is based on a statistical framework, the base and enhancement layers are completely independent, which is an interesting property called codec-independent scalability. Moreover, the introduced DVC scalable schemes show a good robustness to errors as the quality of decoded video steadily decreases with error rate increase. On the other hand, conventional coding exhibits a cliff effect as the performance drops dramatically after a certain error rate value. Further, the issue of privacy protection is addressed for DVC by transform domain scrambling, which is used to alter regions of interest in video such that the scene is still understood and privacy is preserved as well. The proposed scrambling techniques are shown to provide a good level of security without impairing the performance of the DVC scheme when compared to the one without scrambling. This is particularly attractive for video surveillance scenarios, which is one of the most promising applications for DVC. Finally, a practical DVC demonstrator built during this research is described, where the main requirements as well as the observed limitations are presented. Furthermore, it is defined in a setup being as close as possible to a complete real application scenario. This shows that it is actually possible to implement a complete end-to-end practical DVC system relying only on realistic assumptions. Even though DVC is inferior in terms of compression efficiency to the state of the art conventional coding for the moment, strengths of DVC reside in its good error resilience properties and the codec-independent scalability feature. Therefore, DVC offers promising possibilities for video compression with transmission over error-prone environments requirement as it significantly outperforms conventional coding in this case.