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research article

Iron/copper-catalyzed C–C cross-coupling of aryl iodides with terminal alkynes

Volla, Chandra M Rao
•
Vogel, Pierre  
2008
Tetrahedron Letters

Synergic effect of iron and copper salts as catalysts for the Sonogashira–Hagihara cross-couplings of aryl iodides with terminal alkynes is demonstrated. High yields of cross- coupled products are obtained under conditions that are smoother than those using only CuI as catalyst. Furthermore no expensive or/and toxic ligand is required.

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