The power of two! A natural product hybrid (see structure) composed of a siderophore and an antibiotic separated by a poly(ethylene glycol) linker enables the preparation of antimicrobial and cell-resistant surfaces by a simple dip-and-rinse procedure. The anachelin siderophore (left) binds strongly to TiO2 surfaces, and vancomycin is responsible for antibiotic activity.
Détails
Titre
Antimicrobial Surfaces through Natural Product Hybrids
Note
- Highlighted by Medical News Today: http://www.medicalnewstoday.com/articles/117039.php - Highlighted by the Faculty of 1000: http://www.f1000biology.com/article/id/1120405 - Highlighted in ACS Noteworthy Chemistry (15.9.2008): http://portal.acs.org/portal/PublicWebSite/noteworthy/archive/WPCP_010814