The power of two! A natural product hybrid (see structure) composed of a siderophore and an antibiotic separated by a poly(ethylene glycol) linker enables the preparation of antimicrobial and cell-resistant surfaces by a simple dip-and-rinse procedure. The anachelin siderophore (left) binds strongly to TiO2 surfaces, and vancomycin is responsible for antibiotic activity.
Title
Antimicrobial Surfaces through Natural Product Hybrids
Published in
Angewandte Chemie, International Edition
Volume
47
Issue
37
Pages
7123-7126
Date
2008
Note
- Highlighted by Medical News Today: http://www.medicalnewstoday.com/articles/117039.php - Highlighted by the Faculty of 1000: http://www.f1000biology.com/article/id/1120405 - Highlighted in ACS Noteworthy Chemistry (15.9.2008): http://portal.acs.org/portal/PublicWebSite/noteworthy/archive/WPCP_010814
Record creation date
2008-08-03