Antimicrobial Surfaces through Natural Product Hybrids

The power of two! A natural product hybrid (see structure) composed of a siderophore and an antibiotic separated by a poly(ethylene glycol) linker enables the preparation of antimicrobial and cell-resistant surfaces by a simple dip-and-rinse procedure. The anachelin siderophore (left) binds strongly to TiO2 surfaces, and vancomycin is responsible for antibiotic activity.


Published in:
Angewandte Chemie, International Edition, 47, 37, 7123-7126
Year:
2008
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Note:
- Highlighted by Medical News Today: http://www.medicalnewstoday.com/articles/117039.php - Highlighted by the Faculty of 1000: http://www.f1000biology.com/article/id/1120405 - Highlighted in ACS Noteworthy Chemistry (15.9.2008): http://portal.acs.org/portal/PublicWebSite/noteworthy/archive/WPCP_010814
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Note: The status of this file is: EPFL only


 Record created 2008-08-03, last modified 2018-03-17

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