000125293 001__ 125293
000125293 005__ 20190415234759.0
000125293 0247_ $$2doi$$a10.1016/S0065-2660(07)00006-5
000125293 02470 $$2ISI$$a000280569600007
000125293 037__ $$aBOOK_CHAP
000125293 245__ $$aGlobal Control Regions and Regulatory Landscapes in Vertebrate Development and Evolution
000125293 260__ $$bElsevier Inc$$c2008
000125293 269__ $$a2008
000125293 336__ $$aBook Chapters
000125293 490__ $$aAdvances in Genetics$$v61
000125293 520__ $$aDuring the course of evolution, many genes that control the development of metazoan body plans were co-opted to exert novel functions, along with the emergence or modification of structures. Gene amplification and/or changes in the cis- regulatory modules responsible for the transcriptional activity of these genes have certainly contributed in a major way to evolution of gene functions. In some cases, these processes led to the formation of groups of adjacent genes that appear to be controlled by both global and shared mechanisms.
000125293 700__ $$aSpitz, Francois
000125293 700__ $$0240276$$aDuboule, Denis$$g141236
000125293 720_1 $$avan Heyningen, V.$$eed.
000125293 720_1 $$aHill, R. E.$$eed.
000125293 773__ $$j6$$q175-205$$tLong-Range Control of Gene Expression
000125293 8564_ $$zURL
000125293 8564_ $$s2893652$$uhttps://infoscience.epfl.ch/record/125293/files/6_Global%20Control%20Regions%20and%20Regulatory%20Landscapes.pdf$$zn/a
000125293 909C0 $$0252099$$pUPDUB$$xU11705
000125293 909CO $$ooai:infoscience.tind.io:125293$$pSV$$pbook$$pchapter$$qGLOBAL_SET
000125293 937__ $$aUPDUB-CHAPTER-2008-002
000125293 973__ $$aEPFL$$sPUBLISHED
000125293 980__ $$aCHAPTER