Chemical probes shed light on fusion proteins

Site-specific protein labeling with synthetic dyes is an emerging technique for live cell imaging. A protein or peptide tag fused to the protein of interest provides the means for attachment of a fluorophore or other small molecule probe, to allow non-invasive imaging of the dynamics of protein localization. The past two years have seen significant advances in such methods, the publication of a number of new tags for labeling, and the imaginative application of established techniques to tackle previously intractable biological questions.


Published in:
Current Opinion in Structural Biology, 17, 4, 488-494
Year:
2007
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 Record created 2008-06-09, last modified 2018-09-13


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