Tumor-suppressor gene products in cell contacts: the cadherin-APC-armadillo connection
Huelsken, J.; Behrens, J.; Birchmeier, W.
1994

Abstract

Various structural components of intercellular junctions have recently been found to represent (or be related to) products of tumor-suppressor genes. The tumor-suppressor gene product adenomatous polyposis coli (APC) binds to beta 2-catenin (homologous to the product of Drosophila armadillo), which is cytoplasmically associated with the cell adhesion molecule E-cadherin

Details

Title Tumor-suppressor gene products in cell contacts: the cadherin-APC-armadillo connection
Author(s) Huelsken, J. ; Behrens, J. ; Birchmeier, W.
Published in Current Opinion in Cell Biology
Volume 6
Issue 5
Pages 711-716
Date 1994
Note Author address: Max-Delbruck-Center for Molecular Medicine, Berlin, Germany
DOI https://doi.org/10.1016/0955-0674(94)90098-1
Laboratories UPHUELSKEN
Record Appears in Scientific production and competences > SV - School of Life Sciences > ISREC - Swiss Institute for Experimental Cancer Research > UPHUELSKEN - Prof. Huelsken Group
Peer-reviewed publications
Work outside EPFL
Published
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Record creation date 2008-02-13

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