000114910 001__ 114910
000114910 005__ 20190416220434.0
000114910 0247_ $$2doi$$a10.1093/nar/gkj049
000114910 037__ $$aARTICLE
000114910 245__ $$aHTPSELEX--a database of high-throughput SELEX libraries for transcription factor binding sites
000114910 269__ $$a2006
000114910 260__ $$c2006
000114910 336__ $$aJournal Articles
000114910 520__ $$aHTPSELEX is a public database providing access to primary and derived data from high-throughput SELEX experiments aimed at characterizing the binding specificity of transcription factors. The resource is primarily intended to serve computational biologists interested in building models of transcription factor binding sites from large sets of binding sequences. The guiding principle is to make available all information that is relevant for this purpose. For each experiment, we try to provide accurate information about the protein material used, details of the wet lab protocol, an archive of sequencing trace files, assembled clone sequences (concatemers) and complete sets of in vitro selected protein-binding tags. In addition, we offer in-house derived binding sites models. HTPSELEX also offers reasonably large SELEX libraries obtained with conventional low-throughput protocols. The FTP site contains the trace archives and database flatfiles. The web server offers user-friendly interfaces for viewing individual entries and quality-controlled download of SELEX sequence libraries according to a user-defined sequencing quality threshold. HTPSELEX is available from ftp://ftp.isrec.isb-sib.ch/pub/databases/htpselex/ and http://www.isrec.isb-sib.ch/htpselex.
000114910 700__ $$aJagannathan, V.
000114910 700__ $$aRoulet, E.
000114910 700__ $$aDelorenzi, M.
000114910 700__ $$0244404$$aBucher, P.$$g113607
000114910 773__ $$j34$$kSuppl 1$$qD90-4$$tNucleic Acids Res
000114910 8564_ $$s924959$$uhttps://infoscience.epfl.ch/record/114910/files/Nucl.%20Acids%20Res.-2006-Jagannathan-D90-4.pdf$$yPublisher's version$$zPublisher's version
000114910 909C0 $$0252244$$pGR-BUCHER$$xU11780
000114910 909CO $$ooai:infoscience.tind.io:114910$$pSV$$particle$$qGLOBAL_SET
000114910 917Z8 $$x182396
000114910 937__ $$aGR-BUCHER-ARTICLE-2006-003
000114910 973__ $$aOTHER$$rREVIEWED$$sPUBLISHED
000114910 980__ $$aARTICLE