000114902 001__ 114902
000114902 005__ 20190316234108.0
000114902 0247_ $$2doi$$a10.1093/nar/gkh122
000114902 037__ $$aARTICLE
000114902 245__ $$aThe Eukaryotic Promoter Database EPD: the impact of in silico primer extension
000114902 269__ $$a2004
000114902 260__ $$c2004
000114902 336__ $$aJournal Articles
000114902 500__ $$aSwiss Institute of Bioinformatics, Ch. des Boveresses 155, 1066 Epalinges s/Lausanne, Switzerland.
000114902 520__ $$aThe Eukaryotic Promoter Database (EPD) is an annotated non-redundant collection of eukaryotic POL II promoters, experimentally defined by a transcription start site (TSS). There may be multiple promoter entries for a single gene. The underlying experimental evidence comes from journal articles and, starting from release 73, from 5' ESTs of full-length cDNA clones used for so-called in silico primer extension. Access to promoter sequences is provided by pointers to TSS positions in nucleotide sequence entries. The annotation part of an EPD entry includes a description of the type and source of the initiation site mapping data, links to other biological databases and bibliographic references. EPD is structured in a way that facilitates dynamic extraction of biologically meaningful promoter subsets for comparative sequence analysis. Web-based interfaces have been developed that enable the user to view EPD entries in different formats, to select and extract promoter sequences according to a variety of criteria and to navigate to related databases exploiting different cross-references. Tools for analysing sequence motifs around TSSs defined in EPD are provided by the signal search analysis server. EPD can be accessed at http://www.epd. isb-sib.ch.
000114902 700__ $$aSchmid, C. D.
000114902 700__ $$aPraz, V.
000114902 700__ $$aDelorenzi, M.
000114902 700__ $$aPerier, R.
000114902 700__ $$g113607$$aBucher, P.$$0244404
000114902 773__ $$j32$$tNucleic Acids Res$$kSuppl 1$$qD82-5
000114902 8564_ $$uhttps://infoscience.epfl.ch/record/114902/files/Nucl.%20Acids%20Res.-2004-Schmid-D82-5.pdf$$zPublisher's version$$s158122$$yPublisher's version
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000114902 937__ $$aGR-BUCHER-ARTICLE-2004-004
000114902 973__ $$rREVIEWED$$sPUBLISHED$$aOTHER
000114902 980__ $$aARTICLE