000114832 001__ 114832
000114832 005__ 20181203021031.0
000114832 037__ $$aARTICLE
000114832 245__ $$aCCAAT box revisited: bidirectionality, location and context
000114832 269__ $$a1988
000114832 260__ $$c1988
000114832 336__ $$aJournal Articles
000114832 500__ $$aDepartment of Polymer Research, Weizmann Institute of Science, Rehovot, Israel.
000114832 520__ $$aThe so-called CCAAT box is believed to be a major promoter element of higher eukaryotes though it is ill-defined being deduced from very limited sequence data. The comprehensive computer analysis of an unbiased set of 168 promoters presented here removes several of the persisting uncertainties. In particular, it delineates the region of preferential occurrence of the CCAAT element to -110 to -50 relative to the initiation site, suggests that integrity of this pentamer is essential, and confirms bidirectionality as a general property of this element. Within the above region the signal is found to occur in a specific sequence context which is an important supplement to its description.
000114832 700__ $$0244404$$g113607$$aBucher, P.
000114832 700__ $$aTrifonov, E. N.
000114832 773__ $$j5$$tJ Biomol Struct Dyn$$k6$$q1231-6
000114832 909C0 $$xU11780$$0252244$$pGR-BUCHER
000114832 909CO $$pSV$$particle$$ooai:infoscience.tind.io:114832
000114832 937__ $$aGR-BUCHER-ARTICLE-1988-001
000114832 973__ $$rREVIEWED$$sPUBLISHED$$aOTHER
000114832 980__ $$aARTICLE