000112060 001__ 112060
000112060 005__ 20190316234036.0
000112060 0247_ $$2doi$$a10.1063/1.2801625
000112060 022__ $$a0003-6951
000112060 037__ $$aARTICLE
000112060 245__ $$aDirect Measurement of Effective Diffusion Coefficients in Nanochannels Using Steady-State Dispersion Effects
000112060 269__ $$a2007
000112060 260__ $$bAmerican Institute of Physics$$c2007
000112060 336__ $$aJournal Articles
000112060 520__ $$aWe present a method to measure effective diffusion coefficients of fluorescently labeled molecules inside a nanofluidic system. Molecules with small diffusion coefficients show a larger lateral dispersion than highly diffusive species, which is counterintuitive. We performed measurements with wheat germ agglutinin proteins and obtained an effective diffusion coefficient which is four orders of magnitude lower than its free diffusion coefficient. Our technique which is a direct and relatively simple measurement of the effective diffusion coefficients inside nanochannels of well controlled dimensions could help fundamental studies in membranes and separation sciences.
000112060 6531_ $$abiodiffusion
000112060 6531_ $$amicrochannel flow
000112060 6531_ $$amolecular biophysics
000112060 6531_ $$aproteins
000112060 700__ $$aDurand, N. F. Y.
000112060 700__ $$0240202$$g113143$$aBertsch, Arnaud
000112060 700__ $$aTodorova, Mina
000112060 700__ $$aRenaud, Philippe$$g107144$$0240219
000112060 773__ $$j91$$tApplied Physics Letters$$q203106
000112060 8564_ $$uhttps://infoscience.epfl.ch/record/112060/files/S6aa_071115_Published_version.pdf$$zPublisher's version$$s267923$$yPublisher's version
000112060 909C0 $$xU10324$$0252064$$pLMIS4
000112060 909CO $$ooai:infoscience.tind.io:112060$$qGLOBAL_SET$$pSTI$$particle
000112060 917Z8 $$x148230
000112060 937__ $$aLMIS4-ARTICLE-2007-017
000112060 973__ $$rREVIEWED$$sPUBLISHED$$aEPFL
000112060 980__ $$aARTICLE