Disruption of amyloid-derived peptide assemblies through the controlled induction of a beta-sheet to alpha-helix transformation: application of the switch concept
Mimna, Richard; Camus, Marie-Stephanie; Schmid, Adrian; Tuchscherer, Gabriele; Lashuel, Hilal A.; Mutter, Manfred
2007

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Abstract

Reversal of amyloid formation through a controlled induced transformation from beta-sheet to sol. alpha-helix structures through the use of a switch element S could have an important consequences understanding the mechanisms of amyloid formation and clearance.

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Title Disruption of amyloid-derived peptide assemblies through the controlled induction of a beta-sheet to alpha-helix transformation: application of the switch concept
Author(s) Mimna, Richard ; Camus, Marie-Stephanie ; Schmid, Adrian ; Tuchscherer, Gabriele ; Lashuel, Hilal A. ; Mutter, Manfred
Published in Angewandte Chemie, International Edition
Volume 46
Issue 15
Pages 2681-2684
Date 2007
Keywords
Note Reversal of amyloid formation through a controlled induced transformation from beta-sheet to sol. alpha-helix structures through the use of a switch element S could have an important consequences understanding the mechanisms of amyloid formation and clearance.
DOI https://doi.org/10.1002/anie.200603681
Other identifier(s) View record in Web of Science
Laboratories LMNN
LCBP
Record Appears in Scientific production and competences > SV - School of Life Sciences > BMI - Brain Mind Institute > LMNN - Laboratory of Molecular Neurobiology and Neuroproteomics
Scientific production and competences > SB - School of Basic Sciences > SB Archives > LCBP - Laboratory of biomimetic and peptide chemistry
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Record creation date 2007-07-31

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