000109725 001__ 109725
000109725 005__ 20190117192123.0
000109725 02470 $$2ISI$$a000248917500002
000109725 037__ $$aARTICLE
000109725 245__ $$aA virtual valve for smooth contamination-free flow switching
000109725 269__ $$a2007
000109725 260__ $$c2007
000109725 336__ $$aJournal Articles
000109725 520__ $$aWe present a channel geometry that allows for clean switching between different inlets of a microchip without any contamination of the inlets or the downstream flow. We drive this virtual valve with a pneumatic pressure setup that minimizes disturbance of the downstream flow during the switching procedure by simultaneous variation of the pressures applied to the different inlets. We assess the efficiency of the setup by spectroscopic measurement of downstream dye concentrations, and demonstrate its practical utility by sequentially constructing multiple layers of alginate hydrogel. The method is potentially useful for a whole series of further applications, such as changing perfusion liquids for cell culture and cell analysis, metering, chemical- reaction initiation and multi-sample chromatography, to name a few.
000109725 700__ $$0240218$$aBraschler, Thomas$$g157067
000109725 700__ $$aTheytaz, J.
000109725 700__ $$aZvitov-Marabi, Ronit
000109725 700__ $$0240656$$aVan Lintel, Harald$$g117098
000109725 700__ $$aLoche, Grazia
000109725 700__ $$0242554$$aKunze, Anja$$g168829
000109725 700__ $$0240406$$aDemierre, Nicolas$$g129010
000109725 700__ $$aTornay, Raphaël
000109725 700__ $$0240667$$aSchlund, Mario$$g110843
000109725 700__ $$0240219$$aRenaud, Philippe$$g107144
000109725 773__ $$j7$$k9$$q1111-1113$$tLab Chip
000109725 909C0 $$0252064$$pLMIS4$$xU10324
000109725 909CO $$ooai:infoscience.tind.io:109725$$pSTI$$particle
000109725 917Z8 $$x234345
000109725 937__ $$aLMIS4-ARTICLE-2007-004
000109725 973__ $$aEPFL$$rREVIEWED$$sPUBLISHED
000109725 980__ $$aARTICLE