Designing CD4 immunoadhesins for AIDS therapy
Capon, D. J.; Chamow, S. M.; Mordenti, J.; Marsters, S. A.; Gregory, T.; Mitsuya, H.; Byrn, R. A.; Lucas, C.; Wurm, F. M.; Groopman, J. E.
1989

Abstract

A newly-constructed antibody-like molecule containing the gp120-binding domain of the receptor for human immunodeficiency virus blocks HIV-1 infection of T cells and monocytes. Its long plasma half-life, other antibody-like properties, and potential to block all HIV isolates, make it a good candidate for therapeutic use.

Details

Title Designing CD4 immunoadhesins for AIDS therapy
Author(s) Capon, D. J. ; Chamow, S. M. ; Mordenti, J. ; Marsters, S. A. ; Gregory, T. ; Mitsuya, H. ; Byrn, R. A. ; Lucas, C. ; Wurm, F. M. ; Groopman, J. E.
Published in Nature
Volume 337
Issue 6207
Pages 525-31
Date 1989
ISSN 0028-0836
Keywords
Note Department of Molecular Biology, Genentech, Inc., South San Francisco, California 94080.
DOI https://doi.org/10.1038/337525a0
Other identifier(s) View record in PubMed
Laboratories LBTC
Record Appears in Scientific production and competences > SV - School of Life Sciences > SV Archives > LBTC - Cellular Biotechnology Laboratory
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Record creation date 2007-06-05

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