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Abstract

This report will focus on creation of nanostructured PDMS surfaces with tunable feature dimensions and periodicities, and the use of these surfaces to study the influence of nanotopography on cell-substrate interactions. The topography on surfaces is known to influence cell-adhesion and growth behaviour. PDMS is attractive as cell-culture substrate owing to its biocompatibility, ease of structuring, flexibility, tunable hardness and transparency. PDMS is recognized as a promising material for making bioactive bandages that assist in wound healing.

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