Wireless in-body bioelectronics offer powerful biosensing and therapeutic capabilities. Efficient and robust in-body antenna designs are required to ensure a reliable through-body link, increase data rates, and reduce power budgets. This study proposes and demonstrates a pattern- and frequency-reconfigurable capsule-conformal antenna array that responds to the challenges of next-generation in-body bioelectronics. The array comprises two mirrored dual-band elements operating at 434 MHz and 2.45 GHz ISM bands. Tissue-matched dielectric loading of the array improves the radiation efficiency and ensures quasi tissue-independent operation for both bands. Due to the full ground plane, the antenna is shielded from the capsule payload. The achieved efficiencies are compared to the fundamental limitations and closely approach them. The realized gains are -28.9 and -18.6 dBi at 434 MHz and 2.45 GHz, respectively, when the array is placed in the center of a o100-mm diameter spherical phantom with muscle-equivalent properties. Using a single switch, the array can be reconfigured to adjust the angular position of the nulls in the radiation pattern in both bands thereby enabling synthesis of an effectively null-free omnidirectional pattern. The array prototypes are fabricated, and the impedance and far-field radiation patterns are characterized to validate the design in tissue-equivalent liquid phantoms.