Repository logo

Infoscience

  • English
  • French
Log In
Logo EPFL, École polytechnique fédérale de Lausanne

Infoscience

  • English
  • French
Log In
  1. Home
  2. Academic and Research Output
  3. Journal articles
  4. Interspike interval correlation in a stochastic exponential integrate-and-fire model with subthreshold and spike-triggered adaptation
 
research article

Interspike interval correlation in a stochastic exponential integrate-and-fire model with subthreshold and spike-triggered adaptation

Shiau, Liejune
•
Schwalger, Tilo  
•
Lindner, Benjamin
2015
Journal Of Computational Neuroscience

We study the spike statistics of an adaptive exponential integrate-and-fire neuron stimulated by white Gaussian current noise. We derive analytical approximations for the coefficient of variation and the serial correlation coefficient of the interspike interval assuming that the neuron operates in the mean-driven tonic firing regime and that the stochastic input is weak. Our result for the serial correlation coefficient has the form of a geometric sequence and is confirmed by the comparison to numerical simulations. The theory predicts various patterns of interval correlations (positive or negative at lag one, monotonically decreasing or oscillating) depending on the strength of the spike-triggered and subthreshold components of the adaptation current. In particular, for pure subthreshold adaptation we find strong positive ISI correlations that are usually ascribed to positive correlations in the input current. Our results i) provide an alternative explanation for interspike-interval correlations observed in vivo, ii) may be useful in fitting point neuron models to experimental data, and iii) may be instrumental in exploring the role of adaptation currents for signal detection and signal transmission in single neurons.

  • Details
  • Metrics
Type
research article
DOI
10.1007/s10827-015-0558-4
Web of Science ID

WOS:000354102500010

Author(s)
Shiau, Liejune
Schwalger, Tilo  
Lindner, Benjamin
Date Issued

2015

Publisher

Springer

Published in
Journal Of Computational Neuroscience
Volume

38

Issue

3

Start page

589

End page

600

Subjects

Stochastic activity

•

Models of spiking neuron

•

Models of spike-frequency adaptation

•

Integrate-and-fire model

•

Interspike-interval correlations

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LCN  
Available on Infoscience
May 29, 2015
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/114149
Logo EPFL, École polytechnique fédérale de Lausanne
  • Contact
  • infoscience@epfl.ch

  • Follow us on Facebook
  • Follow us on Instagram
  • Follow us on LinkedIn
  • Follow us on X
  • Follow us on Youtube
AccessibilityLegal noticePrivacy policyCookie settingsEnd User AgreementGet helpFeedback

Infoscience is a service managed and provided by the Library and IT Services of EPFL. © EPFL, tous droits réservés