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  4. Learning the structure of genetic network dynamics : A geometric approach
 
conference paper

Learning the structure of genetic network dynamics : A geometric approach

Porreca, R.
•
Cinquemani, E.
•
Lygeros, J.
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2011
IFAC Proceedings Volumes
18th IFAC World Congress

This work concerns the identification of the structure of a genetic network model from measurements of gene product concentrations and synthesis rates. In earlier work, for a wide family of network models, we developed a data preprocessing algorithm that is able to reject many hypotheses on the network structure by testing certain monotonicity properties of the models. Here we develop a geometric analysis of the method. Then, for a relevant subclass of genetic network models, we extend our approach to the combined testing of monotonicity and convexity-like properties associated with the network structures. Theoretical achievements as well as performance of the enhanced methods are illustrated by way of numerical results.

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Type
conference paper
DOI
10.3182/20110828-6-IT-1002.01578
Author(s)
Porreca, R.
Cinquemani, E.
Lygeros, J.
Ferrari-Trecate, G.
Date Issued

2011

Published in
IFAC Proceedings Volumes
Volume

44

Issue

1

Start page

11654

End page

11659

Editorial or Peer reviewed

REVIEWED

Written at

OTHER

EPFL units
SCI-STI-GFT  
Event nameEvent placeEvent date
18th IFAC World Congress

Milan, Italy

Aug. 28 - Sept. 2, 2011

Available on Infoscience
January 10, 2017
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/132593
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