The invention concerns a device configured for electrophysiological analyses of biological entities such as for instance organoids and spheroids. The device comprises a passive first polymer layer (301), a hydrogel layer (302) capable of changing shape upon a trigger stimulus. An array of conductive tracks (400) and contact pads (401) may be used to contact the biological entity by triggering shape change of the hydrogel layer (302). The device may be arranged in a sample well.