African urban agriculture (UA) has garnered attention for its contributions to food security and socio-economic improvement. However, its impact on the psychological well-being of farmers has received minimal focus. This study explores the psychosocial effects of UA by surveying 733 farmers in Dar es Salaam and Greater Lomé. Utilizing the Mental Health Continuum–Short Form (MHC-SF) and bespoke questionnaires, our research evaluates the emotional benefits of urban farming. Findings from regression analyses and spatial assessments conducted using Python and QGIS 3.32.2-Lima indicate significant variations in UA-related happiness across different city zones, with peripheral farmers experiencing greater satisfaction than their urban counterparts. Notably, female farmers reported higher levels of happiness, underscoring UA’s potential to empower women. This study advocates for the integration of UA into urban planning frameworks to foster psychologically beneficial urban environments.