Noble metals such as gold and silver have been used extensively for a range of plasmonic applications, including enhancing the fluorescence rate of a dye molecule, as evidenced by numerous experiments over the past two decades. Recently, a variety of doped semiconductors have been proposed as alternative plasmonic materials, exhibiting plasmonic resonances from ultraviolet to far-infrared. In this work, we investigate the suitability of these alternative materials for enhancing the fluorescence of a molecule. Considering nanosized spheres, we study their response under plane wave illumination and the resulting enhancement factors when coupled to a quantum emitter. Comparisons with standard plasmonic metals reveal that semiconductor materials lead to a significantly reduced, and often strongly quenched, emission of light caused by their dominant absorption, which hinders fluorescence enhancement. However, we show that enhancement may be obtained when considering poor emitting dyes and high refractive index environments. Our findings demonstrate that these alternative materials result in weaker fluorescence enhancement compared to their plasmonic counterparts. Nonetheless, there are means to compensate for this, and a reasonable enhancement can be achieved for dyes in the infrared spectrum.