Following up a two-day invitation-only expert workshop in Geneva on the subject of Trust and Precision Medicine, IRGC published a workshop report in April 2018. This report addresses the concept of trust and conditions of trustworthiness in each of the three stages or components of the precision medicine value chain: data collection, data analysis and provision of medical care. It suggests some recommendations for strategies that earn and provide evidence of trustworthiness, and sustain public trust around precision medicine, including communication, transparency and ways to assess trust.