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  4. Local field potentials in primate motor cortex encode grasp kinetic parameters
 
research article

Local field potentials in primate motor cortex encode grasp kinetic parameters

Milekovic, Tomislav  
•
Truccolo, Wilson
•
Gruen, Sonja
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2015
Neuroimage

Reach and grasp kinematics are known to be encoded in the spiking activity of neuronal ensembles and in local field potentials (LFPs) recorded from primate motor cortex during movement planning and execution. However, little is known, especially in LFPs, about the encoding of kinetic parameters, such as forces exerted on the object during the same actions. We implanted two monkeys with microelectrode arrays in the motor cortical areas MI and PMd to investigate encoding of grasp-related parameters in motor cortical LFPs during planning and execution of reach-and-grasp movements. We identified three components of the LFP that modulated during grasps corresponding to low (0.3-7 Hz), intermediate(similar to 10-similar to 40 Hz) and high (similar to 80-250 Hz) frequency bands. We show that all three components can be used to classify not only grip types but also object loads during planning and execution of a grasping movement. In addition, we demonstrate that all three components recorded during planning or execution can be used to continuously decode finger pressure forces and hand position related to the grasping movement. Low and high frequency components provide similar classification and decoding accuracies, which were substantially higher than those obtained from the intermediate frequency component. Our results demonstrate that intended reach and grasp kinetic parameters are encoded in multiple LFP bands during both movement planning and execution. These findings also suggest that the LFP is a reliable signal for the control of parameters related to object load and applied pressure forces in brain-machine interfaces. (C) 2015 Elsevier Inc. All rights reserved.

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Type
research article
DOI
10.1016/j.neuroimage.2015.04.008
Web of Science ID

WOS:000355002900031

Author(s)
Milekovic, Tomislav  
Truccolo, Wilson
Gruen, Sonja
Riehle, Alexa
Brochier, Thomas
Date Issued

2015

Publisher

Elsevier

Published in
Neuroimage
Volume

114

Start page

338

End page

355

Subjects

Macaque

•

Motor cortex

•

Kinetics

•

Grasping

•

Local field potentials

•

Movement planning

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
UPCOURTINE  
Available on Infoscience
September 28, 2015
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/119218
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