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  4. In Phantom Validation of Time-Domain Near-Infrared Optical Tomography Pioneer for Imaging Brain Hypoxia and Hemorrhage
 
conference paper

In Phantom Validation of Time-Domain Near-Infrared Optical Tomography Pioneer for Imaging Brain Hypoxia and Hemorrhage

Jiang, J.
•
Lindner, S.  
•
Di Costanzo-Mata, A.
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January 1, 2021
Oxygen Transport To Tissue Xlii
42nd Annual Meeting of the International-Society-on-Oxygen-Transport-to-Tissue (ISOTT)

The neonatal brain is a vulnerable organ, and lesions due to hemorrhage and/or ischemia occur frequently in preterm neonates. Even though neuroprotective therapies exist, there is no tool available to detect the ischemic lesions. To address this problem, we have recently designed and built the new time-domain near-infrared optical tomography (TD NIROT) system - Pioneer. Here we present the results of a phantom study of the system performance. We used silicone phantoms to mimic risky situations for brain lesions: hemorrhage and hypoxia. Employing Pioneer, we were able to reconstruct accurately both position and optical properties of these inhomogeneities.

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Type
conference paper
DOI
10.1007/978-3-030-48238-1_54
Web of Science ID

WOS:000754521300054

Author(s)
Jiang, J.
Lindner, S.  
Di Costanzo-Mata, A.
Zhang, C.
Charbon, E.  
Wolf, M.
Kalyanov, A.
Date Issued

2021-01-01

Publisher

SPRINGER INTERNATIONAL PUBLISHING AG

Publisher place

Cham

Published in
Oxygen Transport To Tissue Xlii
ISBN of the book

978-3-030-48238-1

978-3-030-48236-7

Series title/Series vol.

Advances in Experimental Medicine and Biology; 1269

Start page

341

End page

346

Subjects

Medicine, Research & Experimental

•

Physiology

•

Research & Experimental Medicine

•

Physiology

•

time-domain near-infrared optical tomography (td nitor)

•

diffuse optical tomography

•

tissue optical properties reconstruction

•

tissue oxygenation

•

preterm brain imaging

•

reconstruction

•

preterm

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

Event nameEvent placeEvent date
42nd Annual Meeting of the International-Society-on-Oxygen-Transport-to-Tissue (ISOTT)

Albuquerque, NM

Jul 28-31, 2019

Available on Infoscience
February 28, 2022
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/185855
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