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  4. Carbon Dioxide as the C1 Source for Direct C−H Functionalization of Aromatic Heterocycles
 
research article

Carbon Dioxide as the C1 Source for Direct C−H Functionalization of Aromatic Heterocycles

Vechorkin, Oleg  
•
Hirt, Nathalie
•
Hu, Xile  
2010
Organic Letters

A simple and straightforward method has been developed for the direct carboxylation of aromatic heterocylces such as oxazoles, thiazoles, and oxadiazoles using CO2 as the C1 source. The reactions require no metal catalyst and only Cs2CO3 as the base. A good functional group tolerance is achieved.

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Type
research article
DOI
10.1021/ol101450u
Web of Science ID

WOS:000280398900074

Author(s)
Vechorkin, Oleg  
Hirt, Nathalie
Hu, Xile  
Date Issued

2010

Publisher

American Chemical Society

Published in
Organic Letters
Volume

12

Issue

15

Start page

3567

End page

3569

Subjects

Transition-Metal Complexes

•

Copper-Catalyzed Arylation

•

Chemoselective Carboxylation

•

Alkenylboronic Esters

•

Aryl Bromides

•

Co2

•

Palladium

•

Bonds

•

Heteroarenes

•

Reagents

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LSCI  
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/51712
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