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research article

A generalised framework for detailed classification of swimming paths inside the Morris Water Maze

Vouros, Avgoustinos
•
Gehring, Tiago V.
•
Szydlowska, Kinga
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2018
Scientific Reports

The Morris Water Maze is commonly used in behavioural neuroscience for the study of spatial learning with rodents. Over the years, various methods of analysing rodent data collected during this task have been proposed. These methods span from classical performance measurements to more sophisticated categorisation techniques which classify the animal swimming path into behavioural classes known as exploration strategies. Classification techniques provide additional insight into the different types of animal behaviours but still only a limited number of studies utilise them. This is primarily because they depend highly on machine learning knowledge. We have previously demonstrated that the animals implement various strategies and that classifying entire trajectories can lead to the loss of important information. In this work, we have developed a generalised and robust classification methodology to boost classification performance and nullify the need for manual tuning. We have also made available an open-source software based on this methodology.

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Type
research article
DOI
10.1038/s41598-018-33456-1
Author(s)
Vouros, Avgoustinos
Gehring, Tiago V.
Szydlowska, Kinga
Janusz, Artur
Tu, Zehai
Croucher, Mike
Lukasiuk, Katarzyna
Konopka, Witold
Sandi, Carmen
Vasilaki, Eleni
Date Issued

2018

Publisher

Nature Research

Published in
Scientific Reports
Volume

8

Issue

1

Article Number

15089

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LGC  
FunderGrant Number

FNS

176206

Available on Infoscience
October 10, 2018
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/148782
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