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research article
Use of constant denaturant capillary electrophoresis of pooled blood samples to identify single-nucleotide polymorphisms in the genes (Scnn1a and Scnn1b) encoding the alpha and beta subunits of the epithelial sodium channel
2002
The epithelial sodium channel (ENaC) is composed of three homologous subunits: alpha, beta, and gamma. Mutations in the Scnn1b and Scnn1g genes, which encode the beta and the gamma subunits of ENaC, cause a severe form of hypertension (Liddle syndrome). The contribution of genetic variants within the Scnn1a gene, which codes for the alpha subunit, has not been investigated.
Type
research article
Authors
Xue, Ming-Zhan
•
Bonny, Olivier
•
•
Bochud, Murielle
•
Mooser, Vincent
•
Thilly, William G.
•
Schild, Laurent
•
Leong-Morgenthaler, Phaik-Mooi
Publication date
2002
Published in
Volume
48
Issue
5
Start page
718
End page
728
Subjects
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
November 6, 2012
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