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  4. Native Architecture of the Centriole Proximal Region Reveals Features Underlying Its 9-Fold Radial Symmetry
 
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research article

Native Architecture of the Centriole Proximal Region Reveals Features Underlying Its 9-Fold Radial Symmetry

Guichard, Paul  
•
Hachet, Virginie
•
Majubu, Norbert
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2013
Current Biology

Centrioles are cylindrical microtubule-based structures whose assembly is critical for the formation of cilia, flagella, and centrosomes. The centriole proximal region harbors a cartwheel that dictates the 9-fold symmetry of centrioles. Although the cartwheel architecture has been recently analyzed, how it connects to the peripheral microtubules is not understood. More generally, a high-resolution view of the proximal region of the centriole is lacking, thus limiting understanding of the underlying assembly mechanisms.

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Type
research article
DOI
10.1016/j.cub.2013.06.061
Web of Science ID

WOS:000330098200030

Author(s)
Guichard, Paul  
•
Hachet, Virginie
•
Majubu, Norbert
•
Neves, Aitana
•
Demurtas, Davide
•
Olieric, Natacha
•
Fluckiger, Isabelle
•
Yamada, Akinori
•
Kihara, Kumiko
•
Nishida, Yuichiro
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Date Issued

2013

Published in
Current Biology
Volume

23

Issue

17

Start page

1620

End page

1628

Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
UPGON  
Available on Infoscience
August 13, 2013
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/94115
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